Biochemistry and Molecular Biology

By: Md. Al-Tareq Mia

RESEARCH INTEREST
Biochemistry, Cell and Molecular Biology, Lipid and Exercise 

AREA OF EXPERTISE

• Biochemical tests: UV-vis spectroscopy, PCR, ELISA, Gel electrophoresis, ESR, Gram staining, DNA isolation, etc.
• Bio-statistical tests: Avogadro, SPSS, Pymol, PyRx, Pubmed, ExPASY, etc.

PUBLICATIONS

1. MAT Mia, MG Mosaib, MI Khalil, MA Islam, SH Gan, Potentials and safety of date palm fruit against diabetes: A Critical Review, Foods. 2020 Nov; 9(11): 1557. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693939/

By: Md. Abu Rayhan

RESEARCH INTEREST
Cancer Theranostic, Nano Drug Delivery System, Cell and Molecular Biology, Lipid and Exercise Biochemistry

PUBLICATIONS

1. Rayhan MA, et al. Biopolymer and Biomaterial Conjugated Iron Oxide Nanomaterials as Prostate Cancer Theranostic Agents: A Comprehensive Review. Symmetry. 2021; 13(6):974. https://doi.org/10.3390/sym13060974
2. Rayhan MA, et al. Remedial role of exercise training to deep-fried oil-induced metabolic and histological changes in Wistar rats (2020). J Food Biochem. 2020; e13458. doi: 10.1111/jfbc.13458
3. Islam MK, Rayhan MA, et al. Effect of raw and repeatedly fried mustard oil intake on metabolic and organ histological changes in Wistar rat. J Food Biochem. 2019; 44 (2): e13120. doi:10.1111/jfbc.1312

AREA OF EXPERTISE (Laboratory)

• Toxicological Study (In-vivo on rats and mice).
• Retro-orbital/ Blood Collection and Serum Separation
• Organ Collection of rats (Liver, Heart, Lung, Kidney, Intestine, Brain, Small Intestine) and
• Fluorescence Microscopy
• Cell Culture/sub-culture (bacterial and fungal).
• Enzyme (cellulase) production, characterization, and formulation
• Cell Culture/sub-culture (bacterial and fungal)
• Manuscript writing, data presentation and interpretation, and publication

WORK AND RESEARCH EXPERIENCE

1. Lecturer (June’ 2023 – present)
   Dept. of Biochemistry & Molecular Biology, Gono University, Savar, Dhaka, Bangladesh
2. Scientist, Research, and Development at ENZA Bioscience (Nov’ 2020 – Sept’ 2022)
   Tongi, Gazipur, Bangladesh; Main Office: 154 Ridge St, Winchester, MA 01890, USA
3. Graduate Research Assistant (2019-2020)
   Laboratory of Lipid Research and Exercise Biochemistry,
   Dept. of Biochemistry & Molecular Biology, Jahangirnagar University, Dhaka, Bangladesh

GRANTS, AWARDS, AND SCHOLARSHIPS

1. Government Talent Scholarship of Govt. Republic of Bangladesh for securing a position among the top 15 students in the entire university at the undergraduate level (2019)
2. National Science and Technology (NST) Fellowship, issued by the Ministry of Science & Technology, Government of the People’s Republic of Bangladesh (2019)
3. Jahangirnagr University Merit Scholarship in each year of bachelor’s degree (2014-2018)
4. Aklima Anwar Trust Fund Scholarship for obtaining the highest cGPA in the faculty of biological Science, JU (2017)
5. Genius Scholarship by Center for Zakat Management (CZM), Bangladesh (2013-2015)

By: Md. Nafij Mashrur

PUBLICATIONS

1. Yirgu T, Mengistu S, Geleti D, and Mashrur MN. (2023). Herbage yield evaluation of sesbania tree legume lines (Sesbania scopoli) under supplemental irrigation. Int. J. Agric. Vet. Sci., 5(3), 36-43. https://doi.org/10.34104/ijavs.023.0360043

TRAINING AND EXTRA COURSES

• “Basic Techniques of Molecular Identification of Bacteria/Fungi” Organized by INVENT Tech. Ltd.
• “Intellectual Property & Management” authorized by the Institute of Business & Economic Research, United International University, Bangladesh.
• “National Agri-Scientific Conference-2020” Organized by IAAS, Bangladesh.
• “Data Science” is authorized by IBM and offered through Coursera.
• “Python Basics” is authorized by the University of Michigan and offered through Coursera.
• “Introduction to the Biology of Cancer” is authorized by Johns Hopkins University and offered through Coursera.
• “Antimicrobial resistance – theory and methods” authorized by the Technical University of Denmark (DTU) and offered through Coursera.
• “Bacteria and Chronic Infections” authorized by the University of Copenhagen and offered through Coursera.
• “How to Write and Publish a Scientific Paper (Project-Centered Course)” authorized by École Polytechnique and offered through Coursera.
• “COVID-19 detection by RT-PCR” authorized by the Network of Young Biotechnologists in Bangladesh.

RESEARCH SKILLS

DNA Extraction; DNA Amplification, Qualification & Quantifications; Biochemical Tests; In Silico Studies; Fermentations and In Vitro Culture; CMCase Assay; Microscopic Visualization, Data Analysis in R-studio.

 

By: Dr. Farjana Yeasmin Khusbu

1. Altannavch Nyamsambuu, Ashfaque Ahmed, Farjana Yeasmin Khusbu, Sarangerel Oidovsambuu, Md Asaduzzaman Khan, Xi Zhou, Jun-Jiang Fu, Han-Chun Chen. Anti-oxidant and Antiproliferative Activities of Mongolian Medicinal Plant Extracts and Structure Isolation of Gnetin – H Compound. Medicinal Chemistry. (2020). 
2. Jiaqi Xu, Xuanmeng Zhu, Xi Zhou, Farjana Yeasmin Khusbu, Changbei Ma. Recent advances in the bioanalytical and biomedical applications of DNA-templated silver nanoclusters. TrAC Trends Anal. Chem. 124(2020), 115786.
3. Farjana Yeasmin Khusbu, Xi Zhou, Mridul Roy, Fang-Zhi Chen, Qian Cao, Han-Chun Chen. Resveratrol-induced depletion of TRAF6 suppresses prostate cancer cell growth and migration. Int. J. Biochem. Cell Biol. 118(2020), 105644.
4. Xi Zhou, Farjana Yeasmin Khusbu, HanchunChen, Changbei Ma. A turn-on fluorescence assay of alkaline phosphatase activity based on an enzyme-triggered conformational switch of G-quadruplex. Talanta. 208(2020), 120453.
5. Farjana Yeasmin Khusbu, Xi Zhou, Hanchun Chen, Changbei Ma, Kemin Wang. Thioflavin T as a fluorescence probe for biosensing applications. TrAC Trends Anal. Chem. 109(2018) 1-18.
6. Farjana Yeasmin Khusbu, Fang‐Zhi Chen, Han‐Chun Chen. Targeting ubiquitin specific protease 7 in cancer: A deubiquitinase with great prospects. Cell Biochem Funct. 36(5) (2018) 244-254.
7. Xiafei Jiang, Haisheng Liu, Farjana Yeasmin Khusbu, Changbei Ma, Anqi Ping, Qiling Zhang, Kefeng Wu, Mingjian Chen. Label-free detection of exonuclease III activity and its inhibition based on DNA hairpin probe. Anal. Biochem. 555(2018) 55-58
8. Mingjian Chen, Farjana Yeasmin Khusbu, Changbei Ma, Kefeng Wu, Han Zhao, Hanchun Chen and Kemin Wang. A sensitive detection method of carcinoembryonic antigen based on dsDNA-templated copper nanoparticles. New J. Chem. 42(2018) 13702.
9. Pan Gu, Gehou Zhang, Zhiyi Deng, Zhenwei Tang, Huifang Zhang, Farjana Yeasmin Khusbu, Kefeng Wu, Mingjian Chen, Changbei Ma. A novel label-free colorimetric detection of L-histidine using Cu2+-modulated G-quadruplex-based DNAzymes. Spectrochim Acta A Mol Biomol Spectrosc. 203(2018) 195-200.

Abstracts & Oral Presentation in International Conference:

Farjana Yeasmin Khusbu, Fares Abdullah Mohammed Omar Alnaqeb, Altannavch Nyamsambuu, Han Chun Chen. Effects of resveratrol on prostate cancer by modulating the activity of E3 ubiquitin ligase TRAF6. Hunan Provincial Biochemistry and Molecular Biology Annual Conference 2017, Zhangjiajie, Hunan.

By: Sonia Akter

Training Summary
1) Computer, Hasan computer training center in M/S Word, Excel, PowerPoint, Internet Browsing at Dhamrai Dhaka in 2021, duration 3 Months.
2) Industrial Training, Gonoshasthaya Pharmaceutical Ltd (GPL) in oral dosage preparations of Solid, Liquid, and Semi-Solid Pharmaceuticals, Ophthalmic Preparation, and instruments used in the Quality Control having the main focus on HPLC-based instrumentations of the equipment.
3) Workshop at Gono Bishwabidyalay, topic: How to Write Research proposal in 2020, duration 1 day.

By: Md. Yousuf Ali (on study leave, USA)

1. Md Yousuf Ali, Zakia Akter, Zhiqiang Mei, Meiling Zheng, Mousumi Tania, Md. Asaduzzaman Khan, “Thymoquinone in autoimmune diseases: Therapeutic potential and molecular mechanisms.” Journal of Biomedicine & Pharmacotherapy (Publisher: Elsevier). ISI indexed and Impact factor 4.545. Published on 25 Dec 2020. https://www.sciencedirect.com/science/article/pii/S0753332220313500
2. Md Yousuf Ali, Abu Ali Ibn Sina, Shahad Saif Khandker, Lutfun Neesa, Alamgir Kabir, E. M. Tanvir, Md. Ibrahim Khalil and Siew Hua Gan “Nutritional Composition and Bioactive Compounds in Tomatoes and Their Impact on Human Health and Disease: A Review.” Journal of Foods (MDPI publisher). ISI indexed and Impact factor 4.092. Published on 26 Dec 2020. https://www.mdpi.com/2304-8158/10/1/45
3. Yousuf Ali, Alamgir Kabir, Shahad Saif Khandker, Tareq Hossan, Md. Salman Shakil, Md. Aminul Islam, Md. Sakib Hossen, Md. Ashraful Hasan, Siew Hua Gan, and Md. Ibrahim Khalil “Assessment of toxicity and therapeutic effects of goose bone in a rat model”. Journal of Chemistry. https://www.hindawi.com/journals/jchem/2019/1943601/
4. Yousuf Ali, Nur-E Noushin Rumpa, Paul, Sudip, E. M. Tanvir, Md Sakib Hossen, Moumoni Saha, Siew Hua Gan, and Md Ibrahim  Khalil. “Antioxidant properties and sub-acute toxicity evaluation of methanolic extract of pomelo (Citrus grandis L. Osbeck) in Long Evan rats”. Journal of Toxicology. https://www.hindawi.com/journals/jt/2019/2529569/
5. Yousuf Ali, Md. Reaz Morshed, Md. Sakib Hossen, E. M. Tanvir, Alamgir Kabir, Md. Aminul Islam, Nurul Karim, Nadia Alam, Md. Ibrahim Khalil and Siew Hua Gan. “Antioxidant Properties and Dose-Dependent Effects of Monkey Fruits (Artocarpus lakoocha) against Paracetamol-Induced Hepato-Renal Toxicity in Rat” American Journal of Pharmacology and Toxicology 2018. https://thescipub.com/abstract/10.3844/ajptsp.2018.16.29
6. Yousuf Ali, Sudip Paul, E. M. Tanvir, Md. Sakib Hossen, Md. Aminul Islam, Nur-E-Noushin Rumpa, Nikhil Chandra Bhoumik, Md. Sabir Hossain, Moumoni Saha, MI Khalil, and Siew H. Gan,. “Anti-hyperglycemic, antidiabetic and antioxidant effects of Garcinia pedunculata in rats.” Evidence-Based Complementary and Alternative Medicine 2017 (2017). https://www.hindawi.com/journals/ecam/2017/2979760/
7. Sudip Paul, Yousuf Ali, Nur-E. Rumpa, E. M. Tanvir, Md Sakib Hossen, Moumoni Saha, Nikhil Chandra Bhoumik, Siew Hua Gan, and MI Khalil. “Assessment of Toxicity and Beneficiary Effects of Garcinia pedunculata on the Hematological, Biochemical, and Histological Homeostasis in Rats.” Evidence-Based Complementary and Alternative Medicine 2017 (2017). https://www.hindawi.com/journals/ecam/2017/4686104/
8. Solayman, Yousuf Ali, Fahmida Alam, Asiful Islam, Nadia Alam, MI Khalil, and Siew Hua Gan. “Polyphenols: potential future arsenals in the treatment of diabetes.” Current pharmaceutical design 22, no. 5 (2016): 549-565. https://www.ncbi.nlm.nih.gov/pubmed/26601968
9. Md Sakib, Md Yousuf Ali, M. H. A. Jahurul, Mohamed M. Abdel-Daim, Siew Hua Gan, and MI Khalil. “Beneficial roles of honey polyphenols against some human degenerative diseases: a review.” Pharmacological Reports (2017). https://www.ncbi.nlm.nih.gov/pubmed/29128800
10. Md Sakib, E. M. Tanvir, Sudip Paul, Maruf Billah Prince, Moumoni Saha, Yousuf Ali, Siew Hua Gan, Md Ibrahim Khalil, and Nurul Karim. “Protective mechanism of turmeric (Curcuma longa) on carbofuran-induced hematological and hepatic toxicities in a rat model.” Pharmaceutical Biology 55, no. 1 (2017): 1937-1945. https://www.tandfonline.com/doi/full/10.1080/13880209.2017.1345951
11. Solayman, Md Islam, Sudip Paul, Yousuf Ali, Siew Hua Gan and MI Khalil “Physicochemical properties, minerals, trace elements, and heavy metals in honey of different origins: a comprehensive review.” Comprehensive Reviews in Food Science and Food Safety 15, no. 1 (2016): 219-233. https://onlinelibrary.wiley.com/doi/full/10.1111/1541-4337.12182
12. Md Sakib, Sudip Paul, Maruf Billah Prince, Fahmida Alam, Moumoni Saha, Yousuf Ali , E. M. Tanvir, Siew Hua Gan, Md. Ibrahim Khalil. Ganodermalucidum (GL) andAuriculariapolytricha (AP) mushrooms protectagainst carbofuran-induced toxicity in rats. Evidence-Based Complementary and Alternative Medicine 2017 (2017). https://www.hindawi.com/journals/ecam/2018/6254929/

Achievements

• Class eight talent pool Scholarship.
• University Scholarship in all four academic years.
• National Science and Technology (NST) Fellowship 2015-16

Research Experiences

• Research Student (March 2014 – November 2015): Laboratory of Preventive and Integrative Bio-medicine, Department of Biochemistry and Molecular Biology, JU
• Research Associate (November 2016- October 2018): Laboratory of Preventive and Integrative Bio-medicine, Department of Biochemistry and Molecular Biology, JU.
• Consultant Biochemist (October 2018-February 2020): Medinova Medical Services Ltd.

1 2 3 next »